UKPDS 60

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UKPDS 60: risk of stroke in type 2 diabetes estimated by the UK Prospective Diabetes Study risk engine.

BACKGROUND AND PURPOSE People with type 2 diabetes are at elevated risk of stroke compared with those without diabetes. Relative risks have been examined in earlier work, but there is no readily available method for predicting the absolute risk of stroke in a diabetic individual. We developed mathematical models to estimate the risk of a first stroke using data from 4549 newly diagnosed type 2 ...

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The UKPDS: a diabetes nursing perspective

Blood glucose control Improved blood glucose control in type 2 diabetes substantially decreased the risk of microvascular complications (retinopathy and nephropathy), but not macrovascular disease (e.g. myocardial infarction, stroke). There was no difference in overall risk reduction among the different intensive treatment groups, suggesting that improved glycaemic control was the principal fac...

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The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56).

A definitive model for predicting absolute risk of coronary heart disease (CHD) in male and female people with Type II diabetes is not yet available. This paper provides an equation for estimating the risk of new CHD events in people with Type II diabetes, based on data from 4540 U.K. Prospective Diabetes Study male and female patients. Unlike previously published risk equations, the model is d...

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Life-expectancy projection by modelling and computer simulation (UKPDS 46).

A method is described for estimating the life-expectancy of cohorts of type 2 diabetic patients, based on computer simulation from a parametric model. The method can be used where non-parametric methods, such as the Kaplan-Meier estimate, fail due to lack of the data. The simulation algorithm combines observed and modelled information to estimate the life-expectancy implications of event rates ...

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Erectile dysfunction, microangiopathy and UKPDS risk in type 2 diabetes.

BACKGROUND Erectile dysfunction (ED) is a frequent comorbidity in patients with type 2 diabetes mellitus (T2DM), and is now increasingly considered a surrogate marker of endothelial dysfunction as well as a sentinel predictor of new-onset macroangiopathic events. Less attention, however, has been directed at the potential association of ED and microangiopathy in hyperglycaemic states. METHODS...

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ژورنال

عنوان ژورنال: Stroke

سال: 2002

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000020091.07144.c7